(2R)-2-[(tert-butoxycarbonyl)amino]-3-methylbutanoate
N-Boc-D-valine
CAS: 22838-58-0
Molecular Formula: C10H19NO4
(2R)-2-[(tert-butoxycarbonyl)amino]-3-methylbutanoate - Names and Identifiers
| Name | N-Boc-D-valine |
| Synonyms | Boc-D-valine Boc-D-Val-OH N-Boc-D-valine N-t-Boc-D-valine N-a-t-Boc-D-valine t-Butoxycarbonyl-D-va BOC-D-VALINE extrapure N-Boc-D-valineBoc-D-Val-OH N-(tert-Butoxycarbonyl)-D-valine S-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic aci (2R)-2-[(tert-butoxycarbonyl)amino]-3-methylbutanoate |
| CAS | 22838-58-0 |
| EINECS | 1533716-785-6 |
| InChI | InChI=1/C10H19NO4/c1-6(2)7(8(12)13)11-9(14)15-10(3,4)5/h6-7H,1-5H3,(H,11,14)(H,12,13)/p-1/t7-/m1/s1 |
| InChIKey | SZXBQTSZISFIAO-SSDOTTSWSA-N |
(2R)-2-[(tert-butoxycarbonyl)amino]-3-methylbutanoate - Physico-chemical Properties
| Molecular Formula | C10H19NO4 |
| Molar Mass | 217.26 |
| Density | 1.1518 (rough estimate) |
| Melting Point | 164-165 °C |
| Boling Point | 357.82°C (rough estimate) |
| Specific Rotation(α) | 6.25 º (c=1, acetic acid) |
| Flash Point | 160.5°C |
| Solubility | DMSO, Methanol |
| Vapor Presure | 1.42E-05mmHg at 25°C |
| Appearance | White or white-like crystals |
| Color | White |
| BRN | 2050408 |
| pKa | 4.01±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 6 ° (C=1, AcOH) |
| MDL | MFCD00038282 |
(2R)-2-[(tert-butoxycarbonyl)amino]-3-methylbutanoate - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29241990 |
(2R)-2-[(tert-butoxycarbonyl)amino]-3-methylbutanoate - Introduction
N-Boc-D-valine(N-Boc-D-valine) is a chemical substance that has the following properties:
1. Appearance: usually white crystalline powder.
2. Solubility: soluble in some organic solvents, such as ether, alcohol and chlorinated hydrocarbons. Low solubility in water.
3. Chemical properties: a protective group of amino acids, BOC Group and D-valine by esterification reaction. The BOC group can be removed under certain conditions by reagents such as hydrofluoric acid (HF) or trifluoroacetic acid (TFA).
The main uses of N-Boc-D-valine are as follows:
1. Synthetic chemistry: as an intermediate for the synthesis of polypeptides and proteins, D-valine residues are introduced into the polymeric amino acid chain.
2. Pharmaceutical research: used in organic synthesis and biochemical research in drug discovery and development.
3. Chemical analysis: It can be used as a standard substance to analyze and detect the content and properties of D-valine.
The method for preparing N-Boc-D-valine is usually by reacting D-valine with BOC acid (Boc-OH) under alkaline conditions. The specific reaction conditions will be adjusted according to the experimental requirements.
For safety information, N-Boc-D-valine is a chemical that needs to be handled and stored properly. Direct contact with eyes, skin and respiratory tract should be avoided. Appropriate personal protective equipment, such as lab gloves and goggles, should be provided when used. During storage and handling, relevant safe operating procedures should be followed and stored in a sealed container, away from ignition and oxidizing agents. Seek immediate medical help if touched or ingested by mistake.
1. Appearance: usually white crystalline powder.
2. Solubility: soluble in some organic solvents, such as ether, alcohol and chlorinated hydrocarbons. Low solubility in water.
3. Chemical properties: a protective group of amino acids, BOC Group and D-valine by esterification reaction. The BOC group can be removed under certain conditions by reagents such as hydrofluoric acid (HF) or trifluoroacetic acid (TFA).
The main uses of N-Boc-D-valine are as follows:
1. Synthetic chemistry: as an intermediate for the synthesis of polypeptides and proteins, D-valine residues are introduced into the polymeric amino acid chain.
2. Pharmaceutical research: used in organic synthesis and biochemical research in drug discovery and development.
3. Chemical analysis: It can be used as a standard substance to analyze and detect the content and properties of D-valine.
The method for preparing N-Boc-D-valine is usually by reacting D-valine with BOC acid (Boc-OH) under alkaline conditions. The specific reaction conditions will be adjusted according to the experimental requirements.
For safety information, N-Boc-D-valine is a chemical that needs to be handled and stored properly. Direct contact with eyes, skin and respiratory tract should be avoided. Appropriate personal protective equipment, such as lab gloves and goggles, should be provided when used. During storage and handling, relevant safe operating procedures should be followed and stored in a sealed container, away from ignition and oxidizing agents. Seek immediate medical help if touched or ingested by mistake.
Last Update：2024-04-09 20:02:46
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Product Name: Boc-D-valine Visit Supplier Webpage Request for quotationCAS: 22838-58-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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